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Key Activities in the Division of Rheumatology, University Hospitals of Geneva
The Division of Rheumatology is the Center of reference for Rheumatic diseases in the State of Geneva and includes a 20-bed inpatient unit and an outpatient clinic. The clinical expertise of the Division of Rheumatology includes all the aspect of the speciality from inflammatory immune-mediated diseases to degenerative disease and back pain. Specific outpatient activities include chiropractic medicine, musculoskeletal ultrasound, rheumatic foot disorders, and management of musculo-skeletal
disorders in musicians.
The research activities of the Division of Rheumatology include :
Basic studies on cytokine biology and mechanisms of inflammation by using several experimental models of arthritis in the mouse. The laboratory is using and has
generated several lines of transgenic and knockout mice to examine the role of
different cytokines of the IL-1 family in models of arthritis and other experimental models of inflammation.
Host-pathogen interactions during reactive arthritis associated to Chlamydia trachomatis infection, in particular the role of the innate immune responses and the balance between T lymphocyte helper (Th)1, Th2, and Th17 responses in vivo and ex vivo.
We investigate the effectiveness and safety of biological and non-biological
treatments in rheumatoid arthritis using the data collected by the Swiss Clinical Quality Management (SCQM) cohort. We also examine the role of environmental
factors in the progression of rheumatoid arthritis using clinical and radiographic dataobtained from the SCQM cohort.
In collaboration with different nits of the Institution, we have created a
multidisciplinary program (PRODIGE®) for patients with subacute back pain with
the aim of decreasing the long-term disability. We also investigate different aspect of back pain and sciatica through international and local collaborations. Finally, clinical trials are performed to examine the role of inflammation in the pathogenesis of acute sciatica
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